It's the best selling adventure game of all time, so, to be expected it is also the most ported and most remade adventure game of all time. The original release occurred on September 24, 1993. An updated version was released in May 2000, titled Myst: Masterpiece Edition. In November 2000, RealMyst, a remake of the game in full 3D, was released. On February 5, 2014, an remake of RealMyst was released, titled RealMyst: Masterpiece Edition. This version featured improved graphics, and ran on the Unity Engine.
The Windows version of Myst and Myst: Masterpiece Edition is now supported by ScummVM, a program designed to let 2D adventure games run on multiple platforms. With ScummVM, Myst now runs on modern versions of windows, as well as Linux, Mac OS X, and many consoles such as Dreamcast, Wii, PlayStation 2, and PlayStation Portable. For a complete list of platforms supported by ScummVM, see here.