Star Trek: 25th Anniversary is an adventure game with moments of space combat that was released in 1992. All of the members of the main cast of the original Star Trek reprised their roles for this game. It is broken up into several episodes to mimic the format of the show, and is presented in a manner as to act as the fourth year of the five year mission of the USS Enterprise.
There are also action games with the same title that were released for the NES and Gameboy. Other than the title, they have nothing in common with one another.